Kenneth B.Liegner MD a*Judith R.Shapiro MD b* David Ramsay MD c Alan J.Halperin MD d Wayne Hogrefe PhD e Lilly Kong DVM e
2008
http://www.sciencedirect.com/science/ar ... 229370043S
Erythema migrans recurred in a patient 6 months after a course of treatment with minocycline for Lyme disease. Polymerase chain reaction on heparinized peripheral blood at that time demonstrated the presence of Borrelia burgdorferi-specific DNA. The patient was seronegative by Lyme enzyme-linked immunosorbent assay but showed suspicious bands on Western blot. Findings of a Warthin-Starry stain of a skin biopsy specimen of the eruption revealed a Borrelia-compatible structure. Reinfection was not believed to have occurred. Further treatment with minocycline led to resolution of the erythema migrans.